抄録
In our laboratory, effect of Ar + laser irradiation on the activity of frog sciatic nerve, especially thecompound action potential(CAP)and the law of polar excitation, were investigated. During the laserkmadiation(Continuous Wave, 514mm, 50mW), CAP showed a significant decrease in amplitude. Theattenuation speed in CAP amplitudes of anode break excitation (AE) was clearly larger than that ofcathode circuit-closed excitation (CE) on the law of polar excitation. It is reported by some papers thatattenuation in CAP amplitude is based on the influence of the heat generated by laser irradiation.
In this study, heat changes of the nerve specimen surface and inside were measured usingthermography and thermocouple in order to consider the heat influence on the nerve activity by laserirradiation.