Local scour in front of a quay wall due to a jet flow is investigated using a three-dimensional two-way coupled fluid-sediment interaction model (FSM). Numerical results computed using FSM are analyzed and compared with experimental data measured in hydraulic tests. A model parameter involving the sediment transport and the boundary condition of the wall are determined in such a way that the root mean square error of the final seabed profile is minimized for a reference case. The predictive capability of FSM is validated against experimental data in terms of average flow velocity along the jet flow, excess pore-water pressure in the seabed, and final seabed profiles. The effectiveness of filter units against local scour and resulting instability of the wall is demonstrated in terms of excess pore-water pressure predicted using FSM.