2019 Volume 45 Issue 4 Pages 141-146
Conversion of N-acetyl-D-glucosamine (GlcNAc) to furan derivatives in ionic liquid ([Bmim]Cl) was studied with Amberlyst 45 (Brønsted acid) and B(OH)3 (Lewis acid) additives. A 10 wt% of GlcNAc solution in [Bmim]Cl with additives was loaded into a glass reactor and heated at constant temperature in the range of 110–150°C for 5–30 min. In the presence of Amberlyst 45, 80% conversion of GlcNAc was obtained. With both additives, the formation of 3-acetamide-5-acetylfuran was observed. From the reaction kinetics, the activation energy of GlcNAc conversion was determined to be 43.7 kJ/mol with Amberlyst 45 and 73.6 kJ/mol with B(OH)3.