1976 Volume 2 Issue 4 Pages 416-421
Metabolic coefficients in a living system were elucidated in the form of a signal flow diagram. Based upon negative signs of the coefficients, an analytical method was proposed to predict both enzyme activities in loops and conversion amount at a confluent point in metabolic pathways.
It was found that enzymatically activated loops and confluents varied depending on the growth phases in batch culture of yeast cells, i.e. adaptive, accelerative, logarithmic and stationary. It was also observed that the metabolic activities of yeast cells changed radically with some intervals of time. Predicted enzymatic activities in loops and confluents were discussed and compared with the other experimental data reported.