Isolation Rate and Susceptibilities of Candida Species from Blood, Vascular Catheter, Urine and Stool

Abstract

We evaluated species distribution and antifungal susceptibility of Candida isolates during 2002-2008. Of 177 Candida isolates from blood, species distribution was 90 (51％) Candida albicans, 30 (17％) C. parapsilosis,22 (12％) C. glabrata,6(3％)C. tropicalis and 29 (16％) other Candida spp.. Of 162 Candida isolates from vascular catheter, species distribution was 87 (54％) C. albicans,14(9％)C. parapsilosis, 36 (22％) C. glabrata,5(3％),C. tropicalis,2(1％)C. krusei and 18 (11％) other Candida spp.. Of 1889 Candida isolates from urine, species distribution was 1165 (62％) C. albicans, 22(1％) C. parapsilosis, 484 (26％) C. glabrata, 83(4％) C. tropicalis, 26(1％) C. krusei and 109 (6％) other Candida spp.. Of 782 Candida isolates from stool, species distribution was 425 (54％) C. albicans, 3(1％) C. parapsilosis, 103 (13％) C. glabrata, 28(4％) C. tropicalis, 5(1％), C. krusei and 218 (28％) other Candida spp.. Both C. albicans and non-Candida spp. isolated from urine increased slightly over the past 7 years. Flucytosine, fluconazole, itraconazole and micafungin still have strong activity against Candida isolates.