2019 年 93 巻 6 号 p. 768-774
Fusobacterium species have been notable as a cause of Lemierreʼs syndrome. Portal vein thrombosis due to Fusobacterium bacteremia is uncommon. It is sometimes referred to as Lemierreʼs syndrome variant of the gut. We describe herein an 87-year-old man who presented with a fever and chills. Computerized axial tomography with contrast material revealed portal vein thrombosis and a sign of ascending colon diverticulitis. Blood cultures turned positive 75 hours after admission, and Fusobacterium nucleatum was isolated in two sets of anaerobic bottles. He received intravenous antimicrobial therapy with anticoagulation therapy. However, anticoagulation therapy was discontinued because of hematochezia. He underwent colonoscopy and colon cancer in an early stage was diagnosed. We discuss the entry site of F. nucleatum including a possible association between F. nucleatum infection and colon cancer. In addition, a literature review was performed and a total of 17 patients with pylephlebitis due to Fusobacterium species was identified. The characteristics of patients, complications, entry sources, antimicrobial therapies, anticoagulation therapies, and patientsʼ outcomes are summarized.