感染症学雑誌
Online ISSN : 1884-569X
Print ISSN : 0387-5911
ISSN-L : 0387-5911
症例
門脈化膿性血栓性静脈炎を合併したFusobacterium nucleatum 血流感染症の1 例
石原 あやか島田 薫鈴木 智晴高村 典子多田 勝重石岡 春彦矢野(五味) 晴美
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2019 年 93 巻 6 号 p. 768-774

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Fusobacterium species have been notable as a cause of Lemierreʼs syndrome. Portal vein thrombosis due to Fusobacterium bacteremia is uncommon. It is sometimes referred to as Lemierreʼs syndrome variant of the gut. We describe herein an 87-year-old man who presented with a fever and chills. Computerized axial tomography with contrast material revealed portal vein thrombosis and a sign of ascending colon diverticulitis. Blood cultures turned positive 75 hours after admission, and Fusobacterium nucleatum was isolated in two sets of anaerobic bottles. He received intravenous antimicrobial therapy with anticoagulation therapy. However, anticoagulation therapy was discontinued because of hematochezia. He underwent colonoscopy and colon cancer in an early stage was diagnosed. We discuss the entry site of F. nucleatum including a possible association between F. nucleatum infection and colon cancer. In addition, a literature review was performed and a total of 17 patients with pylephlebitis due to Fusobacterium species was identified. The characteristics of patients, complications, entry sources, antimicrobial therapies, anticoagulation therapies, and patientsʼ outcomes are summarized.

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© 2019 一般社団法人 日本感染症学会
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