Experimental Studies on the Preventive Effect of Garlic Extract against Infection with Influenza Virus

Abstract

Preventive effect of garlic extract added with vitamine B₁, B₁₂, and liver extracts against influenza infection in mice (ddYS) pernasally inoculated with influenza virus AO/PR 8 strain was studied.
The experiment revealed that the garlic extract, contrary to Japanese encephalitis case, further hightened the preventive effect of influenza vaccines and in the case of using alone it was as effective as vaccines.
In order to analyze that augmented preventive activity against influenza infection, the activity of globulin fraction extracted from the mice was measured. But, no increase has been seen in the activity in that fraction. Then, it is presumed that it is not neutralization antibody but other preventive factor or factors that was prompted to increase.