著明な低蛋白血症を伴なつたクリプトコッカス性髄膜炎の1例

村田 育夫; 斉藤 厚; 広田 正毅; 植田 保子; 堀内 信宏; 中富 昌夫; 堤 恒雄; 森 信興; 那須 勝; 原 耕平; 山本 秀満; 餅田 親子; 猿渡 勝彦

doi:10.11150/kansenshogakuzasshi1970.50.235

A case of cryptococcal meningitis with severe hypoproteinemia

Ikuo MURATA, Atsushi SAITO, Masaki HIROTA, Yasuko UEDA, Nobuhiro HORIUCHI, Masao NAKATOMI, Tsuneo TSUTSUMI, Nobuoki MORI, Masaru NASU, Kohei HARA, Hidemitsu YAMAMOTO, Chikako MOCHIDA, Katsuhiko SAWATARI

Author information

Ikuo MURATA
2nd Department of Internal Medicine, Nagasaki University School of Medicine
Atsushi SAITO
2nd Department of Internal Medicine, Nagasaki University School of Medicine
Masaki HIROTA
2nd Department of Internal Medicine, Nagasaki University School of Medicine
Yasuko UEDA
2nd Department of Internal Medicine, Nagasaki University School of Medicine
Nobuhiro HORIUCHI
2nd Department of Internal Medicine, Nagasaki University School of Medicine
Masao NAKATOMI
2nd Department of Internal Medicine, Nagasaki University School of Medicine
Tsuneo TSUTSUMI
2nd Department of Internal Medicine, Nagasaki University School of Medicine
Nobuoki MORI
2nd Department of Internal Medicine, Nagasaki University School of Medicine
Masaru NASU
2nd Department of Internal Medicine, Nagasaki University School of Medicine
Kohei HARA
2nd Department of Internal Medicine, Nagasaki University School of Medicine
Hidemitsu YAMAMOTO
Municipal Nagasaki Hospital
Chikako MOCHIDA
Department of Central Clinical Laboratory, Nagasaki University School of Medicine
Katsuhiko SAWATARI
Department of Central Clinical Laboratory, Nagasaki University School of Medicine

Keywords: Cryptococcal meningitis, hypoproteinemia

JOURNAL FREE ACCESS

1976 Volume 50 Issue 6 Pages 235-241

DOI https://doi.org/10.11150/kansenshogakuzasshi1970.50.235

Details

Abstract

A 35 year-old female was confirmed as having cryptococcal meningitis by isolation of cryptococcus neoformans from spinal fluid. She was complicated with mitral steno-insufficiency, hypoproteinemia with hypogammaglobulinemia and decreased cellular immunity.
It was revealed by using¹³¹ I-PVP absorption test that hypoproteinemia had been caused by proteinlosing gastroenteropathy due to chronic heart failure.
Because intravenous injection of amphotericin-B caused side effects such as high fever, unconsciousness attack, only spinal injection of amphotericin-B was performed and the patient has still been living for 2 years.
Details of the treatment and clinical course are described in this paper.

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