NO2急性暴露マウスにおける肺の感染防御作用に関する研究 主として肺胞マクロファージ機能の障害と修復について

二木 芳人

doi:10.11150/kansenshogakuzasshi1970.55.71

Kansenshogaku Zasshi

Online ISSN : 1884-569X
Print ISSN : 0387-5911
ISSN-L : 0387-5911

Studies on the Effect of Pulmonary Resistance to Bacterial Infection in Mice after Exposure to Nitrogen Dioxide

With Special Reference to Activities of- Alveolar Macrophages

Yoshihito NIKI

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Keywords: Nitrogen Dioxide, Pulmonary Resistance, Klebsiella Pneumoniae Infection, Alveolar Macrophage, Intracellular Killing

JOURNAL FREE ACCESS

1981 Volume 55 Issue 2 Pages 71-82

DOI https://doi.org/10.11150/kansenshogakuzasshi1970.55.71

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Abstract

It is now well established that nitrogen dioxide (NO₂) impairs pulmonary resistance to airbone Jacterial infection by inhibiting the function of the alveolar macrophage.
In this study I investigated the effect of pulmonary resistance to bacterial infection in mice immediately or 24 hours after exposure to 20 ppm of NO₂ for 18 hours.

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