Bacteriological Study on Preparations of Multi-Drug-Resistant, Lactic Acid Bacteria
Viable Cell Numbers, Drug-Resistancy and Stability of Organisms
1986 Volume 60 Issue 3 Pages 239-243
Details
1986 Volume 60 Issue 3 Pages 239-243
The multi-drug-resistant preparations of lactic acid bacteria commersially available in Japan were studied on their viable cell numbers, drug-resistancy and stability of organisms.
Preparations tested were A (Enterococcus faecalis, powder), A'(E. faecalis, tablet), B (E. faecalis, powder), B'(E. faecalis, tablet), C (mixture of E. faecalis, Lactobacillus acidophilus and Bifidobacteria, powder) and D (mixture of L. acidophilus, L. lactis and Streptococcus lactis, capsule). Among these, B and B'contained the highest viable cell numbers (108.1-8.4 CFU/g) and viable cell numbers of preparation D were the lowest (107.0 CFU/g).
On testing antibiotics-resistancy using aminobenzyl-penicillin (ABPC), tetracycline (TC), chloramphenichol (CP), erythromycin (EM) and cephalexin (CEX), preparations A and A'showed 50-100% resistancy against all antibiotics tested, whereas B, B'and C showed rather little resistancy aganist TC, CP and EM and preparation D showed few resistancy against ABPC and CP.
Preparations B and B' exhibited firm stability in keeping at 40°C for 30 days, preparations A, A' and C lost 50%viability during storage at 30°C for 30 days, whereas preparation D showed marked decrease of its viable cells either at 30°Cor40°C storage.
