1987 Volume 61 Issue 1 Pages 79-86
From 1975 to 1985 in Tokyo and the vicinity, 197 strains of Bordetella pertussis and 16 strains of Bordetella parapertussis isolated from patients of whooping cough. B. parapertussis strains were constituted about 7.5 per cent of the strains isolated from patients.
Serotyping of the 197 strains of B. pertussis were carried out by the slide agglutination test using monospecific factor sera. Eleven strains (5.6%) belonged to serotype 1.2.3, 186 strains (94.4%) to 1.3.
All the isolates of B. pertussis were highly susceptibel to piperacillin and cefoperazone, and also to erythromycin, minocycline, josamycin, latamoxef, tetracycline, amoxicillin, cefotaxime, ampicillin, and chloramphenicol, and were less susceptible to benzylpenicillin, nalidixic acid, cephalothin, streptomycin, cefatrizine, and sulfamonomethoxazol, and least susceptible to cefaclor and cephalexin.
All the isolates of B. parapertussis were highly susceptible to piperacillin, cefoperazone, and minocycline, and also to latamoxef, erythromycin, and tetracycline, and were less susceptible to chloramphenicol, ampicillin, amoxicillin, nalidixic acid, cefotaxime, josamycin, sulfamonomethoxazol, benzylpenicillin, and cephalothin, and least susceptible to cefatrizine, cefaclor, streptomycin, and cephalexin.
No drug-resistant strains were found.
