Kansenshogaku Zasshi
Online ISSN : 1884-569X
Print ISSN : 0387-5911
ISSN-L : 0387-5911
Bacteriological Investigation on an Outbreak of Acute Enteritis associated with Verotoxin-producing Escherichia coli O111: H-
Hiroshi TANAKAMitsuaki OHSETOYasutaka YAMASHITANobuyuki SHINOHARAHiroo INOUEYoshitada SASAKIYoshitoshi KAKIHARATeizo TSUKAMOTOTakashi YUTSUDOYuichi OKUYoshifumi TAKEDA
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1989 Volume 63 Issue 10 Pages 1187-1194

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Abstract

An outbreak of acute enteritis in children aged one to thirty-three months occurred from June 10th to 23rd, 1986, at a private orphanage in Matsuyama City. Twenty-two out of 23 children suffered from diarrhea. Nine of the 22 children excreted bloody stool. Fever and vomiting were observed with a few patients. One of them, a 33-month-old girl, developed hemolytic uremic syndrome, and died twelve days after the admission.
Escherichia coli O111: H- was isolated from fecal specimens of 7 out of 15 patients. The culture filtrate of the isolate caused fluid accumulation in ligated ileal loops in a rabbit, and was lethal to mice.
It wa found that all isolates produced two kinds of Vero toxins (VT1 and VT2, or shiga-like toxin I and II). The amount of VT2 produced in vitro was about 10 times more than that of VT1.

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© The Japansese Association for Infectious Diseases
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