1989 Volume 63 Issue 5 Pages 541-548
Septicemia encounterd at Kawasaki Municipal Hospital between 1985 and 1986 were studied clinically. Forty six patients had monomicrobial and 5 has polymicrobial infections, respectively. Out of these 46 patients with septicemia, 17 were due to Escherichia coli, 7 were due to Klebsiella pneumoniae and 4 were due to Staphylococcus aureus. Ten patients had hepatobiliary, 7 had hematological, 7 had malignant diseases as underlying diseases, respectively. Out of 10 patients complicated with septic shock, 7 died. Twenty three patients were community acquired infections. The age of most of the patients were over 50. The motality rate of more than 6 5-year-old patients were higher than that of other patients. Our of 5 patients with septicemia due to polymicrobials, only 1 patient with erythroleukemia died. Fifty patients were treated mainly with β-lactam antibiotics such as piperacilin or cefmetazole alone or in combination with aminoglycosides and so on
Three patients with infective endocarditis were encountered during this period. Two were due to a-streptococcus and 1 was due to Enterococcus. A 41-year-old patient with mitral valve insufficiency and metastatic gastric carcinoma to the bone marrow were complicated with disseminated intravascular coagulation. This patient, however, was successfully treated with a daily dose of 24 mega units of benzylpenicillin, and was given gabexate mesilate, concomitantly.
