Kansenshogaku Zasshi
Online ISSN : 1884-569X
Print ISSN : 0387-5911
ISSN-L : 0387-5911
Severe Falciparum Malaria with Prolonged Hemolytic Anemia after Successful Treatment with Intravenous Artesunate
Ichiro ITODATakeshi YASUNAMIKen KIKUCHIHisashi YAMAURAKyoichi TOTSUKAKentaro YOSHINAGAMasanao TERAMURAHideaki MIZOGUCHIToshimitsu HATABUShigeyuki KANO
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2002 Volume 76 Issue 8 Pages 600-603

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Abstract

We report a 68-year-old woman with severe falciparum malaria contracted in Tanzania. She presented high parasitemia and was treated successfully with intravenous artesunate, a qinghaosu derivative, and aggressive supportive therapy. She developed hemolytic anemia and jaundice on day 11 and blood transfusion was required. This case illustrates that intravenous artesunate has excellent antimalarial activity with rapid efficacy and that no severe adverse effect but conventional aggressive supportive therapy is still important in the treatment of severe falciparum malaria.

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© The Japansese Association for Infectious Diseases
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