2003 Volume 77 Issue 8 Pages 631-634
Two cases of Haemophilus influenzae type b (Hib) meningitis were occurred continuously in a day nursery. Both isolates obtained from cerebrospinal fluids of 2 patients were β lactamase producing amoxicillin/clavulanic acid sensitive strains. But biotypes and restriction fragment length polymorphism patterns by Sma I digested pulse-field gel electrophoresis of two isolates were different, respectively. Although it was already reported simultaneous occurrence of two cases of Hib meningitis caused by same strain through the nursery contact, none were reported by different strains. It was considered that two colonized strains had caused meningitis in two patients continuously.