肝臓
Online ISSN : 1881-3593
Print ISSN : 0451-4203
ISSN-L : 0451-4203
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治療に難渋した肝性脳症に対するレボカルニチン塩化物の使用経験
津端 俊介小川 光平平野 正明坂牧 僚有賀 諭生山川 雅史
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2014 年 55 巻 1 号 p. 76-78

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We investigated the effects of levocarnitine chloride (L-CA) in cirrhotic patients repeatedly suffering episodes of refractory hepatic encephalopathy. This study included 5 patients with cirrhosis requiring maintenance therapy with BCAA infusion because of recurrent episodes of hepatic encephalopathy despite combined oral medications. The use of L-CA, though at a relatively low dose of 900 mg/day, lowered the serum ammonia level, thereby decreasing the frequency of BCAA infusions in all the patients. These results suggest that L-CA may be a useful treatment choice for patients failing to show symptomatic amelioration in response to conventional therapy regimens.

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© 2014 一般社団法人 日本肝臓学会
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