肝臓
Online ISSN : 1881-3593
Print ISSN : 0451-4203
短報
三重県北中部で持続発生しているE型肝炎の主たる感染株(ヨーロッパ型3e/3sp株)の県内産豚からの特定
岡野 宏赤地 重宏中野 達徳岡本 宏明
著者情報
キーワード: E型肝炎, 豚レバー, HEV遺伝子
ジャーナル フリー

2014 年 55 巻 9 号 p. 553-555

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抄録

The source of European-type subgenotype 3e/3sp hepatitis E virus (HEV) strain that is prevalent in hepatitis E patients in Mie, Japan, remained unknown. The present analyses of stored RNA samples that had been extracted from liver tissues obtained from 85 slaughtered pigs in Mie in 2007, revealed the presence of two HEV strains (swJ-Mie07-37L and swJ-Mie07-80L). The swJ-Mie07-80L strain was classified into subgenotype 3b/3jp, while swJ-Mie07-37L belonged to 3e/3sp and shared high nucleotide sequence identities of 98.3-99.2% with the 3e/3sp strains recovered from hepatitis E patients in Mie during 2004-2012. These results suggest that pigs are important reservoirs for HEV infection even in Mie, although the hepatitis E patients did not recall consuming raw pig liver/intestine before the disease onset.

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© 2014 一般社団法人 日本肝臓学会
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