2018 Volume 59 Issue 4 Pages 224-229
A 40-year-old man had a huge tumor in the left hepatic lobe. The tumor was 12 cm in size, and abdominal computed tomography showed multiple intrahepatic metastases. Magnetic resonance imaging showed a low-intensity area on T1-weighted images and a high-intensity area on T2-weighted images. Esophagogastroduodenoscopy, colonoscopy, and positron emission tomography/computed tomography revealed no other malignancies. A target liver biopsy was performed to obtain a histological diagnosis. On immunohistochemistry, the tumor cells were positive for chromogranin and synaptophysin, and the Ki67 index was 10%. The tumor was histologically diagnosed as a grade 2 neuroendocrine tumor. Primary hepatic neuroendocrine tumors are rare. We herein report a case of a primary hepatic neuroendocrine tumor diagnosed by needle biopsy.