Kanzo
Online ISSN : 1881-3593
Print ISSN : 0451-4203
ISSN-L : 0451-4203
Case Reports
A case of primary hepatic neuroendocrine tumor diagnosed by needle biopsy
Aya KugiyamaShiho MiyaseNatsuki TsukanoHirohumi IwashitaShigetoshi HujiyamaNobuyuki Arima
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2018 Volume 59 Issue 4 Pages 224-229

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Abstract

A 40-year-old man had a huge tumor in the left hepatic lobe. The tumor was 12 cm in size, and abdominal computed tomography showed multiple intrahepatic metastases. Magnetic resonance imaging showed a low-intensity area on T1-weighted images and a high-intensity area on T2-weighted images. Esophagogastroduodenoscopy, colonoscopy, and positron emission tomography/computed tomography revealed no other malignancies. A target liver biopsy was performed to obtain a histological diagnosis. On immunohistochemistry, the tumor cells were positive for chromogranin and synaptophysin, and the Ki67 index was 10%. The tumor was histologically diagnosed as a grade 2 neuroendocrine tumor. Primary hepatic neuroendocrine tumors are rare. We herein report a case of a primary hepatic neuroendocrine tumor diagnosed by needle biopsy.

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© 2018 The Japan Society of Hepatology
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