定期検診でのHCV抗体未測定者におけるHCV抗体の陽性率

抄録

We conducted a retrospective, single-center, observational study to estimate the positive detection rate for HCV antibodies in the people who underwent an HCV antibody test as part of their physical checkup (comprehensive health checkup). The people who underwent the HCV antibody test as part of their comprehensive health checkup at our hospital between April 1, 2014 and March 31, 2017 were included as subjects. Of the 61578 people who underwent a comprehensive health checkup, 3938 people underwent an HCV antibody test (excluding those who underwent the test again), of which 42 people were positive for HCV antibodies, resulting in a positive rate of 1.07%. The positive rate gradually increased with age up to a peak value of 2.54% (12 of 472 subjects) in the age group of 60-64 year olds, and decreased past that age group.

In terms of future issues, it is considered necessary to confirm whether HCV-RNA is detected in the subjects who were positive for HCV antibodies. As almost the same people undergo regular health checkups every year, a new approach from regular health checkups such as going to a local community to provide health checkups is considered necessary in order to more widely detect still undiagnosed patients infected with HCV.