2021 Volume 62 Issue 3 Pages 144-151
The first case was that of a 71-year-old female patient who was referred to our hospital due to a sense of palpitation. Her data were as follows: hemoglobin 7.7 g/dl, haptoglobin less than 10 mg/dl, positivity for Coombs test, which were compatible with autoimmune hemolytic anemia (AIHA). The administration of steroids was effective. One year later, the increases in ALP and gGTP and the positivity of mitochondrial m2 antibody, were recognized. The histology of liver biopsy showed primary biliary cholangitis (PBC) with Nakanuma Stage 2. The second case was that of a 67-year-old male patient who was referred to our hospital due to a brownish color of urine. His data were as follows: hemoglobin 10.3 g/dl, haptoglobin less than 10 mg/dl, positivity for Coombs test, which were compatible with AIHA. The administration of steroids was effective. However, the continuous increases of ALP and gGTP, together with the positivity of mitochondrial m2 antibody were recognized. The histology of the liver biopsy showed PBC with Nakanuma Stage 2. The administration of ursodeoxycholic acid was effective for both cases.
