2021 Volume 62 Issue 5 Pages 229-239
The Liver Imaging Reporting and Data System (LI-RADS) is a comprehensive system for standardizing the terminology, technique, interpretation, reporting, and data collection of liver imaging. LI-RADS was created specifically for patients at risk for hepatocellular carcinoma by experts in liver imaging and supported by the American College of Radiology in the context of surveillance by ultrasonography (US); diagnosis by computed tomography (CT) or magnetic resonance imaging (MRI), or contrast material-enhanced US; and assessment of treatment response by CT or MRI. Additionally, the Li-RADS diagnostic algorithm is integrated into the latest guidelines of the American Association for the Study of Liver Diseases. This article provides 1) a broad overview of LI-RADS v2018, including its relationships to other imaging guidelines, composition, and aims; and 2) detailed description, issues, and future directions of CT/MRI diagnostic LI-RADS.