2024 Volume 65 Issue 11 Pages 533-540
Severe alcoholic hepatitis is a serious form of alcoholic liver disease, presenting as acute-on-chronic liver failure (ACLF). A national survey on ACLF in Japan revealed that 37.2% of the cases were because of severe alcoholic hepatitis, and the 1-month mortality of severe alcoholic hepatitis can reach to 30%-50% without liver transplantation (LT). Anecdotally, a certain period of abstinence is required for listing, although recent studies have demonstrated the effectiveness of early LT for severe alcoholic hepatitis with comparable alcoholic relapse post-LT. Multidisciplinary evaluation of social and psychological aspects and family support contribute to alcoholic relapse post-LT. Therefore, further studies may be warranted to identify the LT eligibility criteria for patients with severe alcoholic hepatitis.
