Abstract
Two autopsy cases of hepatoma with Mallory bodies were reported. The first case (52 years old man) was alcoholics but the second case (59 years old man) had never used alcohol in any form. Histologically, hepatoma of both cases were well differentiated type associated with portal cirrosis and numerous hyaline inclusions were found in the hepatoma cells. Morphological and histochemical examination revealed that these hyaline inclusions were identical with Mallory's alcoholic hyaline.