Abstract
The present investigation was conducted to determine Whether the leucocyte adherence inhibition (LAI) test is useful for the diagnosis of hepatocellular carcinoma (HCC) and serve as an immunological parameter of HCC progress.
LAI test using a tissue extract from liver of HCC as the antigen was conducted on leucocytes from the patients with HCC, liver cirrhosis and the other GI cancer. The rates of nonadherence index were 37, II and -2.3 percent, respectively. Thus, The LAI test Was proved to be useful for the diagnosis of HCC, and was also speoific to HCC When the tissue extract from HCC was used as the antigen.
The LAI test using α-fetoprotein (AFP) as the antigen failed to get leucocyte adherence to glass, therefore, it was concluded that AFP was not the substance which may cause LAI phenomenon.
