1981 Volume 22 Issue 1 Pages 86-90
A 31-year-old female who had a 4 or 5 year history of heavy alcohol ingestion was admitted for evaluation of jaundice and generalized convulsions. At out patient clinic, the hemoglobin was 10.1g/dl, the hematocrit 30.7%, the reticulocytes 53‰, the serum bilirubin 12.1mg/dl (direct 6.4), the serum cholesterol 300mg/dl, the TG 613mg/dl, the GOT 441mU/ml, the GPT 61mU/ml, and the γ-GTP 2090mU/ml.
An osmotic fragility test performed on 7th hospital day was normal and survival halflife for 51Cr erythrocytes were 19 days. A bone marrow aspiration revealed normochromic erythroid hyperplasia and a liver biopsy carried out on 9th hospital day showed alcoholic hepatitis.
Of 36 cases of Zieve's syndrome which had been reported in Japan until 1979, 11 were confirmed a decompensated hemolytic anemia by either osmotic fragility test or survival halflife for 51Cr erythrocytes.
