Kanzo
Online ISSN : 1881-3593
Print ISSN : 0451-4203
ISSN-L : 0451-4203
An autopsy case of idiopathic portal hypertension with hepatic nodular hyperplasia
Hideo TERAOHideyo ITAKURAAkio TAMENISHITatsuo MUNEHISAToshihiko KOJIYasushi UENO
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1981 Volume 22 Issue 3 Pages 434-445

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Abstract

An autopsy case, 59-year old woman, of idiopathic portal hypertension with hepatic nodular hyperplasia and intra- and extrahepatic portal vein thrombosis was presented. Histology, histogenesis, etiological factors and mutual relationship of those three lesions were discussed in this paper.
At autopsy, the liver weighed 640g, and showed atrophy of the left lobe and 'the potato liver" appearance of the right lobe. Microscopically the left lobe of the liver showed obstruction and thrombosis of small radicles of portal veins which were typical findings of idiopathic portal hypertension reported in the literatures. The right lobe showed nodular hyperplasia, in which characteristic finding was the presence of ectopic portal veins. The ectopic portal veins seemed to have played an important role in development of nodular hyperplasia.
Angiograms and scintillation scanning of nodular hyperplasia were presented. Their findings were similar to hepatoma.
The spleen (360g) showed remarkable fibroadenia, Gamna-Gandy body and narrowing of trabecular veins.
Although definite etiology of idiopathic portal hypertension in this case was not revealed, the possible causes were discussed.

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© The Japan Society of Hepatology
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