2002 年 56 巻 3 号 p. 109-119
The purpose of this study is to evaluate two fabrication methods (direct method, indirect method) of a simple AMP and evaluate its treatment effect for the patients with OSAS by using polysomnography (PSG) and Epworth sleepiness scale (ESS) before and after AMP therapy. Thera Snore^<TM> (Distar) was used as AMP in this study. Fabrication method of this AMP was a direct method indicated by the manufacturer. We designed an indirect method and compared it with the direct method. To evaluate the treatment effect of this AMP, five OSAS patients (4 males and 1 female) were involved. Mean age was 59.8 years and body mass index (BMI) was 26.1. Each patient underwent PSG and ESS before and after AMP therapy and evaluated apnea index (AI), apnea-hypopnea index (AHI), Lowest SpO_2, arousal index, and ESS. Our indirect fabrication method was better than direct method from the viewpoint of the fitness and the protection of mucous membrane from scald. AI was improved from 5.5±4.04 to 2.3±3.86. AHI was improved 20.8±14.99 to 8.8±9.04. Lowest SpO_2 was improved from 81.0±9.08% to 86.6±6.73%. Arousal index improved 31.6±10.26 to 25.5±10.37. ESS was improved from 10.6±1.95 to 6.0±3.08. It was suggested that the indirect method was better than the direct method for fabricating the AMP which was used in this study. It was also suggested that this AMP was useful for the treatment of the patients with OSAS.