A Case of Angioimmunoblastic T cell Lymphoma Diagnosed by Rearrangementsof the T-Cell Receptor β-chain

Abstract

A case of angioimmunoblastic T cell lymphoma (AILD) was reported. Clinicaly, generalized lymphadenophathy, skin rash, fever and hypergammaglobulinemia were recognized. The characteristic pathologic changes in lymph nodes were warked proliferated high endotherial venules and polymorphic cells, including lymphocyte, plasma cells, and immunoblasts. And many signals of EBER were detected by in situ hybridization method. T cell receptor β-chain gene rearrangements was occurred in this case. The result supported that AILD is T cell-lymphoma.