The objective of this investigation is to predict the natural frequency of a laminated carbon fiber reinforced thermoplastics (CF/PEEK) plate with a hole by using the finite element method. In the finite element formulation, a parabolic isoparametric plate bending element is used and the first-order shear deformation theory based on the Mindlin type is considered. The good agreement between the numerical and the experimental results of CF/PEEK unidirectional and cross-ply laminated plates with a hole shows that the natural frequencies and modes can be predicted by the present method. Futhermore, the changes of frequencies and modes of the antisymmetrically angle-ply and the cross-ply laminated plates with the size of the hole, the stacking sequence of lamina and the plate length-to-width ratio are examined by F. E. M. under simply supported and clamped boundary conditions.