レーザドップラー振動計と複合顕微鏡の組合せによる内耳蝸牛内基底板振動の計測

抄録

Although the amplitude of tympanic membrane vibrations is only a few manometers when we speak in a low voice, we can understand clearly what is being said. This is speculated to be due to cochlear amplification. However, the mechanism of amplification in the cochlea is obscure. Therefore, in this study, cochlear basilar membrane vibrations in live, dead and hypoxic guinea pigs are measured directly using a laser Doppler vibrometer coupled to a compound microscope, and an attempt is made to clarify the mechanism of cochlear amplification. Results indicate that a cochlear amplifier exists in live guinea pigs and is influenced by a moderate level of hypoxia.