Helical steel cords have been in use as an important and convenient machine element for load and displacement transmission. In various mechanical devices, such as automobiles, helical steel cords have been applied as a kind of simple and mechanical remote operation system. Although helical steel cords have been used widely, the mechanism of fatigue failure has not sufficiently been clarified due to the complicated fracture phenomenon. It is important to understand the fatigue failure mechanism for the optimum design of helical steel cords. The purpose of this study is to clarify the fatigue failure mechanism of helical steel cords. Some experiments and analysis were carried out under tension and bending combined conditions. Especially, the relation between the location of the damaged wires, the failure mode and the cycles to failure were investigated.