INFLUENCE OF AMCHA ON THE ACTIVITY OF FIBRINOLYSIN (PLASMIN)

Abstract

1) Effect of AMCHA upon fibrinolysis, caseinolysis and TAMe esterolysis with plasmin was examined and compared with that of EACA. It is evident that AMCHA has inhibitory activity upon fibrinolysis with plasmin but not caseinolysis and TAMe esterolysis, and the inhibitory activity of AMCHA is approximately 5 times greater than EACA.
2) Inhibitory activity of AMCHA upon activation process of plasminogen was suggested.
3) Enhancing effect of AMCHA and EACA upon fibrinolysis with plasmin and the difference of the action of AMCHA and EACA between the effect upon fibrinolysis with plasmin and caseinolysis or TAMe esterolysis were discussed.