The Keio Journal of Medicine
Online ISSN : 1880-1293
Print ISSN : 0022-9717
High-intensity Focused Ultrasound (HIFU) in the Treatment of Benign Prostatic Hyperplasia (BPH)
Thomas EbertMarkus GraefenStephan MillerDietmar SaddelerBernd Schmitz-DrägerRolf Ackermann
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1995 Volume 44 Issue 4 Pages 146-149


Transurethral resection of the prostate (TURF) and open adenectomy are regarded the golden standard in the management of patients with symptomatic benign prostatic hyperplasia (BPH). Various alternative treatment forms (microwaves, laser, radiofrequency, focused ultrasound) have been introduced recently. They all aim at reduction of morbidity related to TURP keeping a comparable efficacy at the same time. Since December 1992, 50 patients with BPH have been treated by high intensity focused ultrasound (HIFU-P) at our department. Six weeks following HIFU-P mean Qmax improved from 5.7ml/s to 11.6ml/s. Post voiding residual volume (RV) dropped from 215ml to 100 ml, the International Prostate Symptom Score (IPSS) from 19.8 to 9.9. Both, INS and RV further improved during the following weeks. Follow-up data one year after treatment demonstrate that results remained stable in the majority of patients. Urinary tract infections were observed in 3 patients, macrohematospermia in all and macrohematuria (caused by the suprapubic catheter) requiring blood transfusion in 1 patient.

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