Abstract
1) The distribution of blood group P1 antigens in human organs was investigated. P1 antigen was found in blood group P1 kidney. Both group P1 and P2 kidneys contained much P antigens and lung, spleen and heart contained small amount of P antigens.
2) The each fraction corresponding to globoside and CTH (ceramide trihexoside) isolated from kidney showed P and Pk activities respectively.
3) Treatment of the globoside fraction from kidney with human liver's crude enzyme preparation (contained ß-N-acetylgalactosaminidase) caused the loss of P specificity and the appearance of Pk specificity.
As the above results, it was confirmed that blood group P antigens in kidney were identical with those in erythrocytes.
