感染根管治療剤としてのマイシリンとフオルモクレゾールとの比較成績に就て

抄録

141 cases of the opened infected root canals were divided into two groups at random: mycillin group and formocresol group. The root canals of both groups were enlarged and cleaned with Kerr's reamers, and immediately after that, mycillin paper points (contain 3000 unit of penicillin and 2 mg. of strepotmycin) or the paper points with formocresol (1: 1) were inserted into the root canals of the respective group. Then, the effects of these two medicaments were compared in respect of the times of treatment to get sterility of the root canal.
The following results were obtained.
1. Only enlargement by reamers and cleaning by alcohol secured the negative culture in the 11 among 141 cases (7.8%) .
2. Average times of treatment to secure sterility of the canal was 1.75 for mycillin group and 2.13 for f ormocresol group. The difference between those times of treatment was not significant statistically.
3. The number of cases of which the treatment had been abandoned was 16 among 71 cases in mycillin group and 9 among 70 cases in formocresol group. The main reason of abandone of the treatment was acute periodontitis caused after the first application in the former group and the difficulty to get sterility in spite of many times of treatment in the latter.
4. After the application, Gram-positive cocci and bacilli, and Gram-negative bacilli could be observed in the root canals, however, Gram-negative cocci were very rare. Yeasts were observed only in the mycillin group.
5. Some formocresol group showed negative culture, though bacteria were seen at the stained specimens. This was considered that the dead bacteria by the medicaments still have had a tendency to be stained, and that they were visible just like living organisms.
6. It was concluded that for the sterilization of the infected root canals, formocresol had been superior to mycillin.