1997 年 64 巻 4 号 p. 512-517
The purpose of this investigation was to find the relationship between the occurrence of Candida species and mutans streptococci at 7 sites (saliva, tongue, mucosa, teeth, clasp, external, and mucosal denture surfaces) in the mouth of 97 elderly persons (males : 43, age : 76.4± 6.7 years; females : 54, age : 75.0 ± 6.6 years) . Among the subjects, there were complete denture wearers (n=20), partial denture wearers (n = 45), and non-denture wearers (n= 32) .
Candida species were more significantly (p<0.001) predominant in complete and partial denture wearers (80% each) than in non-denture (18.8%) wearers. The presence of Candida was highest on the mucosal denture surfaces followed by clasp, tongue, and remaining teeth in that order. Positive correlations were significantly found between the CFU numbers of Candida species and mutans streptococci present on the external surfaces (p < 0.001), natural teeth (p<0.001), clasp (p<0.01), and saliva (p<0.05) . A negative correlation (r= -0.503 ; p<0.001) was found between the number of teeth and the CFU numbers of Candida species. Moreover, the CFU numbers of both groups of microorganisms also increased in 80-year-old and over persons. Candida species were most predominantly found in persons with poor oral and denture cleanliness.