The Kurume Medical Journal
Online ISSN : 1881-2090
Print ISSN : 0023-5679
A Case of Late-Onset Systemic Lupus Erythematosus with Severe Anemia
MOEKO MATSUMOTOSHINJIRO KAIEDASEIYO HONDAHIROAKI IDATOMOAKI HOSHINOTAKAAKI FUKUDA
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JOURNALS FREE ACCESS Advance online publication

Article ID: MS61004

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Abstract

A 59-year-old woman was referred to our hospital because of severe anemia and leucopenia. Although she developed mild arthralgia without the typical symptoms of systemic lupus erythematosus (SLE), positivity for anti-Sm antibodies led us to a diagnosis of late-onset SLE. Autoimmune hemolytic anemia (AIHA) and suppression of reticulocyte production were considered to have been involved in the etiology of severe anemia. Administration of oral prednisolone (PSL) resulted in a marked improvement of the hematological abnormalities. As late-onset is rare and patients tend to show the typical symptoms less frequently, close attention should be focused on latent symptoms and immunological findings.

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© 2013 Kurume University School of Medicine
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