The Kurume Medical Journal
Online ISSN : 1881-2090
Print ISSN : 0023-5679
ISSN-L : 0023-5679
Advanced Gastric Cancer with Liver Metastasis Effectively Treated by Intra-Hepatic Arterial Infusion of 5-FU, MMC and Peroral Administration of 5-FU: A Case Report
KEISHIRO AOYAGIKIKUO KOUFUJISHOJIRO YANONAOTAKA MURAKAMIYASUHIRO TERASAKIYOSHIYA YAMASAKIJINRYO TAKEDAKAZUO SHIROUZU
Author information
JOURNALS FREE ACCESS

2000 Volume 47 Issue 4 Pages 325-327

Details
Abstract

We have experienced a case of advanced gastric cancer with liver metastasis effectively treated by intra-hepatic arterial infusion of 5-fluorouracil (5-FU), mitomycin C (MMC) and peroral administration of 5-FU. The patient was a 48-year-old male diagnosed as having advanced gastric cancer with multiple liver metastasis in the bilateral lobes of the liver. This patient was treated by intra-hepatic arterial infusion of 5-FU (250 mg/2days × 8 doses), MMC (20 mg × 1 dose, 6 mg/2 weeks × 6 doses) and Peroral administration of 5-FU (200 mg/day). At 14 weeks later, a CT revealed that the metastatic liver tumors had disappeared. However, at 7 months after the therapy, the patient eventually died of liver and brain metastasis. These results suggested that intra-hepatic arterial infusion of 5-FU and MMC was an effective therapy for metastatic tumors in the liver, but we need to perform intra-hepatic arterial infusion using a new prolonged regimen to treat the liver metastasis.

Information related to the author
© THE KURUME MEDICAL JOURNAL
Previous article Next article
feedback
Top