1971 年 2 巻 2 号 p. 99-102
Recently, for the benefit of nonblaze and nonexplosion, the inhalations anesthetics which have chemical constructions of C, Cl and F have been used generally. But, it is reported that by using these anesthetics in the room which is not well ventilated and when there are blazes, the mucous membrances of eyes and nose are irritated with light headaches. So, it may be assumed that the cause of these symptoms might occur from the poisonous gases which are derived by the decomposition of the anesthetic gases coming in contact with the blaze in the room. For the investigation of the above question, the authors checked the outbreak of the poisonous gases from the inhalations anesthetic gas using Fluothane ([chemical formula] : Takeda Pharmacy Company). Phosgene 0.002-0.02ppm. and hydrogen-chloride gas 300ug. per 10ml. of Fluothane vapor which passed through high temperature were recognized. The authors also felt the irritation of the noses and eyes, which may come from the hydrogen-chloride gas. Two young rats were laid in the glass bottle which were filled by Fluothane vapor according to the above mentioned condition for histological examination, but no reactions showed in their lungs, tracheas and bronchi by phosgene, chloride and hydrogenchloride gases.