A Case of Laryngotracheal Stenosis Induced by Cicatricial Pemphigoid

Abstract

Cicatricial pemphigoid is an intractable autoimmune disease characterized by blisters and erosions, leaving scars in the mucous membranes of the mouth, conjunctiva, pubic region, etc. The mucous membranes of the larynx and trachea are also affected in rare cases. Recently, we experienced a case of cicatricial pemphigoid that induced lesions in the mucous membranes of the larynx and trachea in addition to other mucosal membranes. The patient was a 45-year-old female whose main complaints were dry cough, hoarseness, lacrimation, and vulval ulceration. Since the disease appeared to be resistant to steroid therapy, double filtration plasmapheresis was performed. This treatment stabilized the symptoms, allowing reduction of steroid dosage. A new form of treatment for this disease is needed.