2015 Volume 56 Issue 1 Pages 135-139
This study establishes a toxicity assessment of the mixture of Fe3+, Mn2+, and Al3+ ions by employing a Probit dose-response model and an augmented simplex design. The toxicity of individual Fe3+, Mn2+, and Al3+ metal ions with respect to Escherichia coli DH5α is in the order of Mn2+ > Fe3+ > Al3+. The mixture of Fe3+, Mn2+, and Al3+ ions shows a hump region and a saddle region in the IC50 values contour plot. Fe-Mn-Al ternary alloys may possess a lower toxic risk when the ratio of released metal ions approaches the hump region of the contour plot. Fe-Mn-Al ternary alloys may present an increased toxic risk when the ratio of released metal ions gets close to the saddle regions of the contour plot.