MATERIALS TRANSACTIONS
Online ISSN : 1347-5320
Print ISSN : 1345-9678
Toxicity Assessment of Fe-Mn-Al Ternary Alloys Using a Probit Dose-Response Model and an Augmented Simplex Design
Shih-Hang ChangBor-Yann ChenChin-He Chiang
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2015 Volume 56 Issue 1 Pages 135-139

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Abstract

This study establishes a toxicity assessment of the mixture of Fe3+, Mn2+, and Al3+ ions by employing a Probit dose-response model and an augmented simplex design. The toxicity of individual Fe3+, Mn2+, and Al3+ metal ions with respect to Escherichia coli DH5α is in the order of Mn2+ > Fe3+ > Al3+. The mixture of Fe3+, Mn2+, and Al3+ ions shows a hump region and a saddle region in the IC50 values contour plot. Fe-Mn-Al ternary alloys may possess a lower toxic risk when the ratio of released metal ions approaches the hump region of the contour plot. Fe-Mn-Al ternary alloys may present an increased toxic risk when the ratio of released metal ions gets close to the saddle regions of the contour plot.

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© 2014 The Japan Institute of Metals and Materials
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