総説
オートファジーによるオルガネラの選択的分解：酵母における ERファジーおよびヌクレオファジーの発見
2017 年 42 巻 5 号 p. 181-185
詳細
2017 年 42 巻 5 号 p. 181-185
Autophagy is an intracellular degradation pathway, in which degradation targets are sequestered by a double membrane vesicle called the autophagosome, transported to, and degraded in the lysosome or vacuole. Recent studies revealed that some organelles, such as mitochondria and peroxisomes, are marked by “autophagy receptors”, and selectively engulfed by the autophagosome. Here, I describe our recent discovery of selective autophagy of the endoplasmic reticulum and nucleus in the budding yeast Saccharomyces cerevisiae.
