β₂ ミクログロブリン透析除去膜の設計

抄録

Due to a rapid technological progress in hemodialysis treatment, lifespan of uremic patient has been longer in recent years. Hemodialysis is now expected not only to save or support the life but also to promise a more comfortable life for the patient. For a more comfortable life, hemodialysis related complications become an important problems. Among complications, amyloidosis caused by β₂-microglobulin is regarded as a serious problem.
In this report, a new concept of hemodialysis membrane for β₂-microglobulin removal was described in terms of membrane pore control by membrane surface-protein interaction as well as membrane manufacturing.