National Trends in the Distribution of Candida Species Causing Candidemia in Japan from 2003 to 2014 A Report by the Epidemiological Investigation Committee for Human Mycoses in Japan

Hiroshi Kakeya; Koichi Yamada; Yukihiro Kaneko; Katsunori Yanagihara; Kazuhiro Tateda; Shigefumi Maesaki; Yoshio Takesue; Kazunori Tomono; Jun-ichi Kadota; Mitsuo Kaku; Yoshitsugu Miyazaki; Katsuhiko Kamei; Kazutoshi Shibuya; Yoshitiho Niki; Minoru Yoshida; Yoshihiro Sei

doi:10.3314/mmj.17-00014

Special Article

National Trends in the Distribution of Candida Species Causing Candidemia in Japan from 2003 to 2014

A Report by the Epidemiological Investigation Committee for Human Mycoses in Japan

Hiroshi Kakeya, Koichi Yamada, Yukihiro Kaneko, Katsunori Yanagihara, Kazuhiro Tateda, Shigefumi Maesaki, Yoshio Takesue, Kazunori Tomono, Jun-ichi Kadota, Mitsuo Kaku, Yoshitsugu Miyazaki, Katsuhiko Kamei, Kazutoshi Shibuya, Yoshitiho Niki, Minoru Yoshida, Yoshihiro Sei

著者情報

Hiroshi Kakeya
Department of Infection Control Science, Osaka City University Graduate School of Medicine, Osaka
Koichi Yamada
Department of Infection Control Science, Osaka City University Graduate School of Medicine, Osaka
Yukihiro Kaneko
Department of Bacteriology, Osaka City University Graduate School of Medicine, Osaka
Katsunori Yanagihara
Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki
Kazuhiro Tateda
Department of Microbiology and Infectious Diseases, Toho University Omori Medical Center, Tokyo
Shigefumi Maesaki
Department of Infectious Disease and Infection Control, Saitama Medical University, Saitama
Yoshio Takesue
Department of Infection Control and Prevention, Hyogo Medical College Hospital, Hyogo
Kazunori Tomono
Department of Infection Control and Prevention, Osaka University Graduate School of Medicine, Osaka
Jun-ichi Kadota
Departments of Respiratory medicine and Infectious disease, Oita University Faculty of Medicine, Oita
Mitsuo Kaku
Department of Infection Control and Laboratory Diagnostics, Tohoku University Graduate School of Medicine, Miyagi
Yoshitsugu Miyazaki
Department of Chemotherapy and Mycoses, National Institute of Infectious Diseases, Tokyo
Katsuhiko Kamei
Division of Clinical Research, Medical Mycology Research Center, Chiba University, Chiba
Kazutoshi Shibuya
Department of Pathology, Omori Hospital, Toho University School of Medicine, Tokyo
Yoshitiho Niki
Development for Clinical Infectious Diseases, Showa University, Tokyo
Minoru Yoshida
Department of Internal Medicine IV, Teikyo University School of Medicine, University Hospital, Mizonokuchi, Tokyo
Yoshihiro Sei
Department of Dermatology, Teikyo University School of Medicine, University Hospital, Mizonokuchi, Tokyo

キーワード: blood stream infections, Candida, candidemia, Japan

ジャーナルフリー

2018 年 59 巻 1 号 p. E19-E22

DOI https://doi.org/10.3314/mmj.17-00014

詳細

抄録

The Epidemiological Investigation Committee for Human Mycoses in Japan performed a retrospective epidemiological survey of candidemia and causative Candida species. Data from 2003 to 2014 were collected from 10 Japanese university hospitals. A total of 328,318 blood cultures were included. The prevalence of fungi in all cultures and in positive cultures were 0.58±0.09% and 4.46±0.66%, respectively. Among the results that were positive for Candida species (N=1,921), Candida albicans was the most common species (39.5%) and was followed by Candida parapsilosis (23.3%), Candida glabrata (13.2%), Candida tropicalis (7.1%), Candida krusei (3.2%), and others (13.7%). During the last 6 years, the frequency of C. albicans has significantly decreased in Japan, while that of C. glabrata has increased. Additional surveys are needed to continuously monitor the trends in the distribution of candidemia.

責任著者(Corresponding author)

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