Magnetic Resonance in Medical Sciences
Online ISSN : 1880-2206
Print ISSN : 1347-3182
ISSN-L : 1347-3182
Technical Notes
Estimation of Perilymph Enhancement after Intratympanic Administration of Gd-DTPA by Fast T1-mapping with a Dual Flip Angle 3D Spoiled Gradient Echo Sequence
Shinji NAGANAWAMasahiro YAMAZAKIHisashi KAWAIKiminori BOKURAMichihiko SONETsutomu NAKASHIMA
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JOURNAL OPEN ACCESS

2013 Volume 12 Issue 3 Pages 223-228

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Abstract

Eleven patients with suspected Ménière's disease received intratympanic (IT) administration of gadolinium (gadopentetate dimeglumine; Gd) prior to acquisition of 3-dimensional (3D) fluid-attenuated inversion recovery (FLAIR), 3D real inversion recovery (IR), and fast T1 mapping by dual flip angle 3D gradient echo (FT1-map) imaging sequences to evaluate the degree of perilymph enhancement. Though 3-dimensional FLAIR could detect lower concentrations of gadolinium than 3D real IR, in 2 patients, poor enhancement still prevented visualization of the endolymphatic space using 3D FLAIR. We could predict poor contrast enhancement in these 2 patients using the FT1-map technique.

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© 2013 by Japanese Society for Magnetic Resonance in Medicine
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