The permeability or absorption in the normal live rabbit has been investigated through the determination of the blood levels of various chemical substances infused into the bladder.
The bladder-epithelium of rabbits leave out or absorbe foreign bodies, such as medical drugs, antibiotics and coloring matters, infused into the bladder, out of which are in hypertonic solution, and allows them to transfer into the body-fluid, especially into the blood stream, by its function of absorption or permeability. And the substances that have demonstrated their transference into the blood stream through the normal bladder-epitheliallayers of rabbits are as follows: Invertose, Glucose, 1-ascorbic acid, NaCl, CaCl2, sulfathiazole, sulfadiazine, arsenobenzene-sodium, procaine, hexamethylene-tetramine, P32, penicillin, streptomycin Dihydrostreptomycin, methylene-blue, Uranine, Hepatosulphalein etc.
The velocity of transference of the substances infused into the bladder into the body-fluid is different and there are some variety of absorption.
