1957 年 45 巻 12 号 p. 1297-1314
Using Starr's type ballistic bed modified by H. A. Blaire, cause of the origin of K wave and effects of various depressant agents were studied in arterial hypertension. Keith-Wagener's classification was also investigated hemodynamically. Thus the following results were gained.
1) In hypertension, deepening of K wave and increase in respiratory variation were more frequently observed. K wave was assumed to be the resultant of peripheral arteriolar resistance, of impact wave in the aorta, of bounding wave of the aortic arch and of impact wave of the atrioventricular septum.
2) An acute administration of Pendiomide, Vegolysen-T and Ansolysen reduced stroke volume and minute volume, but JK/IJ was increased in many cases. Apresoline and Methobromine showed frequently the opposite results, however, decrease in the systemic blood pressure did not always correspond to the change of JK/IJ, which would be due to different occurrence of the homeostasis in the medication of different kind of agents.
3) Keith-Wagener's classification established from point of view of the morbid course does not clarify the expression of the decompensated states in hypertensive cases.
As to this question there were performed the statistical and hemodynamical investigations.