CLINICAL STUDIES ON THE BALLISTOCARDIOGRAM

(3 REPORT) BALLISTOCARDIOGRAPHIC RESPONSES IN HYPERTENSIVE PATIENTS TO ACUTE EXPERIMENTS OF DEPRESSOR DRUGS

Abstract

This study concerns the longitudinal and lateral ballistocardiographic responses of 20 hypertensive patients to parenteral administration, in acute experiments, of 1-hydrazino-phthalazine, pentolinium tartarate, benzylimidazoline and amobarbital sodium.
Each drug proved capable of producing a striking changes of abnormal ballistocardio-graphic pattern toward normal and of increasing IJ amplitude in certain patients. With respect to qualitative improvement in the ballistocardiogram the order was: 1-hydrazino-phthalazine, pentolinium tartarate, benzylimidazoline and amobarbital sodium (listed in decreasing order). With respect to increasing of IJ amplitude the following was the order: 1-hydrazinophthalazine, pentolinium tartarate, amobarbital sodium and benzylimidazoline. But the ballistocardiographic changes did not always paralleled the hypotensive response of blood pressure. However, benzylimidazoline produced the marked ballistocardiographic response without lowering the blood pressure.