2016 年 29 巻 1 号 p. 28-33
Purpose: Deep venous thrombosis (DVT) is an important complication for stroke patients, often causing fatal pulmonary thromboembolism. However, factors related to DVT in stroke patients remain unclear. We evaluated factors contributing to DVT in patients with acute stroke.
Methods: Our study included 71 patients with acute-stage stroke, comprising 58 patients with cerebral infarction and 13 patients with cerebral hemorrhage. DVT was diagnosed by ultrasonography within 2 weeks of stroke onset. Associations of DVT with laboratory parameters such as D-dimer and BNP levels, and clinical factors including age, stroke type, level of consciousness, lower limb score of National Institute of Health Stroke Scale (NIHSS), and antithrombotic therapy were assessed.
Results: Among 71 patients with acute stroke, DVT was found in 14 patients. Level of lower limb palsy and D-dimer were significantly higher in the DVT group than in the non-DVT group. Univariate logistic regression analysis revealed NIHSS score ≥2 was associated with increased risk of DVT with an odds ratio of 7.68 (p=0.0117).
Conclusions: Our study results suggest lower limb palsy as a predictor of DVT in patients with acute stroke.