Abstract
In a 47 y/o Japanese woman, facial skin coarseness and general fatigue occurred 3 years before she was seen in our clinic. About the same time, she noticed a generalized pigmentation, in addition to rough neck skin and depigmentation around one congenital and two acquired nevi. She had recently been diagnosed as having a growth hormone producing pituitary tumor (ACTH was normal) and was treated surgically. The generalized pigmentation and acanthosis nigricans improved after the surgery but the Sutton’s nevi remained unchanged. Acromegaly pigmentation and acathosis nigricans were thought to be caused by the growth hormone producing tumor. This may be the first report of Sutton’s nevus associated with above described conditions. The precise relationship remains to be determined.